วันศุกร์ที่ 21 สิงหาคม พ.ศ. 2552

cholesterol and coronary heart disease

cholesterol and coronary heart disease
Coronary Heart Disease (CHD) is the most common cause of morbidity and mortality among the elderly. In Western countries, it accounts for 80 â €" 85 percent of all cardiovascular deaths in older people.

If a person ages, his cardiovascular system is normal and expected changes. These can be age-associated changes in cardiac anatomy, age-associated changes in cardiovascular physiology, and age-related changes in pharmacokinetics and pharmacodynamics.

The presentation of CHD may be increased by these changes, along with other age-related changes in the kidneys, brain and muscle-skeletal systems. Ultimately, the diagnosis and hence the treatment of cardiovascular diseases in the elderly may be more complicated.

Various conventional risk factors for CHD among younger people, such as smoking, hypertension, hyperlipidemia, diabetes mellitus still important factors for the elderly. Moreover, age is a powerful and independent risk factor for CHD. The risk increases when men reach 55 years old and above and women 65 years old and above.

Women have a much lower risk of CHD compared to men, but the sex differential age decreases, as progress. For example, the event will be 1:5 in favor of women over the age of 35 years, but at the age of 70, the ratio is almost 1:1.

Symptoms such as shortness of breath, dizziness or palpitations are frequently used for the CHD in the elderly. Sometimes, musculoskeletal problem in older people it may be that the patient from the exercise in the context complaining angina. Instead of complaining of chest pain during a heart attack, an older patient may be difficulty in breathing or symptom of stroke. Silent myocardial infarction is also common. As reported in the Cardiovascular Health Study and the Framingham Heart Study, approximately 40 percent of heart attack was not recognized in the age group 75 to 84 years.

In the management of heart disease, some diagnostic procedures such as treadmill exercise may not be suitable because of the associated problems common in the elderly. It is also risky to coronary angiography and coronary angioplasty procedures for elderly patients with the presence of reduced kidney function. After a heart attack in hospital mortality and the risk of subsequent reinfarction or its complications in older patients. The use of clot breaking drugs (thrombolytics) has an increased risk of cerebral hemorrhage in the very elderly. Some age-associated changes in the kidney or gastrointestinal function allows the reduction of the normal heart drug doses when medications in elderly patients.

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